Bibliograph

Alzheimer's disease and infectious causes, the theory and evidence, Elaine A. Moore

Type

Label

Alzheimer's disease and infectious causes, the theory and evidence, Elaine A. Moore

Language

eng

Bibliography note

Includes bibliographical references (pages 203-213) and index

Illustrations

illustrations

Index

index present

Literary Form

non fiction

Main title

Alzheimer's disease and infectious causes

Nature of contents

bibliography

Oclc number

1120149204

Responsibility statement

Elaine A. Moore

Series statement

McFarland health topics

Sub title

the theory and evidence

Summary

"With the recent discovery that amyloid beta protein, the cause of plaques in Alzheimer's disease, is an antimicrobial peptide produced in response to infection, many researchers are focusing on the role infection plays in the development of Alzheimer's disease. Brain studies have also identified a number of different viruses, bacteria, fungi, and protozoa in the postmortem brain specimens of Alzheimer's patients. Infection (particularly chronic, latent and persistent infections) causes an immune response that leads to inflammation and brain cell degeneration, which are characteristic features of Alzheimer's disease. Sources of infection in Alzheimer's disease vary from childhood infections to gut microbes that find their way into the brain as a result of aging, leaky gut syndrome, and increased permeability of the blood brain barrier. Studies and ongoing clinical trials show that treatment of viral and bacterial infections, as well as restoring a healthy balance to the gut microbiome, can reduce disease risk and improve symptoms in patients with Alzheimer's disease. This book serves as an introduction to the human microbiome and the role that infection plays in the development of Alzheimer's disease."-Provided by publisher"--, Provided by publisher

Table Of Contents

One-The Mystery of the Mind and Consciousness -- Two-Infection as a Primary Cause of Alzheimer's Disease -- Three-Microorganisms and the Microbiome -- Four-The Immune System, Neurodegeneration -- and the Blood-Brain Barrier -- Five-Alzheimer's Disease: Its Stages and Pathology -- Six-Herpes Viruses in Alzheimer's Disease -- Seven-Other Associated Viruses and the Prion Connection -- in Alzheimer's Disease -- Eight-Bacterial Infections Implicated in Alzheimer's Disease -- Nine-Fungal and Protozoan Infections in Alzheimer's Disease -- Ten-Alzheimer's Disease Risk Factors -- Eleven-Genetic Influences in Alzheimer's Disease -- Twelve-Risk Reduction and Therapies in Alzheimer's Disease

Classification